Figure 3
From: Invasive trophoblast promote stromal fibroblast decidualization via Profilin 1 and ALOX5
ALOX5 inmmunolocalization in first trimester decidua. (a–b) ALOX5 showed nuclear staining in first trimester decidua basalis. (c–e) Immunoflorescence showed ALOX5 did not co-localize with (c). HLAG (EVT marker) but did co-localize with (d). CD68 (macrophage marker) and (e). Vimentin (HESC marker). ALOX5 - green, CD68, Vimentin and HLAG – red. (f–h) Serial sections of first trimester decidua basalis showing that ALOX5 (f) was not present in tissue surrounding EVTs (determined by presence of HLAG; (g). The presence of macrophages in this tissue was confirmed by CD68 staining (h). Insert shows negative control staining.
