Table 1 Genes altered by PFN1 (>2-fold) in decidualized (treated with E+MPA for 10–12 days) HESC stimulated with 100 µM PFN1 for 6 h.

From: Invasive trophoblast promote stromal fibroblast decidualization via Profilin 1 and ALOX5

  

PFN1 treated vs. Control

Fold Change

p-value

Upregulated genes

MYLK2

Myosin light chain kinase 2

2.5757

0.242757

Downregulated genes

ADRB1

Adrenergic, beta-1-, receptor

−3.7308

0.242764

ALOX5

Arachidonate 5-lipoxygenase

−4.2358

0.083988

CNGA2

Cyclic nucleotide gated channel alpha 2

−2.2372

0.257212

DRD5

Dopamine receptor D5

−3.519

0.56862

NOSTRIN

Nitric oxide synthase trafficker

−2.6417

0.346766

NPPC

Natriuretic peptide C

−2.286

0.215343

UTS2R

Urotensin 2

−3.0634

0.12733