Table 1 Genes altered by PFN1 (>2-fold) in decidualized (treated with E+MPA for 10–12 days) HESC stimulated with 100 µM PFN1 for 6 h.
From: Invasive trophoblast promote stromal fibroblast decidualization via Profilin 1 and ALOX5
PFN1 treated vs. Control | |||
---|---|---|---|
Fold Change | p-value | ||
Upregulated genes | |||
MYLK2 | Myosin light chain kinase 2 | 2.5757 | 0.242757 |
Downregulated genes | |||
ADRB1 | Adrenergic, beta-1-, receptor | −3.7308 | 0.242764 |
ALOX5 | Arachidonate 5-lipoxygenase | −4.2358 | 0.083988 |
CNGA2 | Cyclic nucleotide gated channel alpha 2 | −2.2372 | 0.257212 |
DRD5 | Dopamine receptor D5 | −3.519 | 0.56862 |
NOSTRIN | Nitric oxide synthase trafficker | −2.6417 | 0.346766 |
NPPC | Natriuretic peptide C | −2.286 | 0.215343 |
UTS2R | Urotensin 2 | −3.0634 | 0.12733 |