Figure 1
From: Pattern of retinal morphological and functional decay in a light-inducible, rhodopsin mutant mouse
Early effects of bright light exposure. (A,C) Control retinas from Ht Tvrm4 mice before bright light exposure; (B,D) Central retinal sections from Ht Tvrm4 littermates exposed to 12,000 lux for 1 min and examined after 48 hrs. (A,B) Green signal: ICCH for the light sensitive channel of rods; red: ethidium nuclear counterstaining. Note the thinner ONL and the abundance of pycnotic nuclei in (B) (arrow). (C,D) cone arrestin (red) and rhodopsin (green). Clustering of rhodopsin in the outer segments of rods (OS) is evident in (D) where cones are also poorly stained and at a lower density.
