Figure 7
From: A balancing act: RNA binding protein HuR/TTP axis in endometriosis patients
TTP knockdown results in higher levels of TNF-α cytokine: In vitro downstream protein analysis of inflammatory cytokines associated with RNA binding protein regulation in TTP knockdown EECCs. Although mRNA transcripts of TNF-α was significantly higher in control EECCs compared to TTP knockdown cells, the opposite was observed at the protein level using multiplexing (Panel A). Other inflammatory cytokines for IFN-γ, IL-6, IL-12(p70), IL-8 and GM-CSF did not differ at protein level (Panels B–F). Expression data illustrated as mean ± SEM. *P < 0.05. Data is derived from three independent experiments; n = 3.
