Figure 6 | Scientific Reports

Figure 6

From: Anti-AMPA GluA3 antibodies in Frontotemporal dementia: a new molecular target

Figure 6

Effect of GluA3 antibodies in neurons differentiated from human iPSc on Tau and TDP43 expression. (A) Representative WB analysis from homogenates of neurons differentiated from human iPSc and incubated for 24 hours with CSF with (CSF+) or without (CSF−) anti-GluA3 antibodies (dilution 1:100). (B,C) The histogram shows the quantification of the expression levels of Tau (B) and TDP43 (C), normalized on GAPDH; results are expressed as mean±standard errors (SEM), *p < 0.05, paired Student’s t-test.

Back to article page