Figure 7

TEM images of tumor tissues from different treatment groups. (a) Saline; (b) Fe3O4/ICG@PLGA/PFP NPs only; (c) laser irradiation only; and (d) Fe3O4/ICG@PLGA/PFP NPs with laser irradiation. Magnification: 1450×; scale bar, 10 μm. Many generated microbubbles (red arrows) appeared in the tumor tissues. Blue arrows indicate interrupted cells, and yellow arrows indicate red blood cells.