Figure 5 | Scientific Reports

Figure 5

From: Contrast-Enhanced Ultrasound Imaging Quantification of Adventitial Vasa Vasorum in a Rabbit Model of Varying Degrees of Atherosclerosis

Figure 5

Haematoxylin and eosin stained vessel in early atherosclerosis of the high-fat diet group showed fibre hyperplasia and increased new vessels, ×40 (A). Immunohistochemical stain for VEGF of the same vessel showing increased adventitial microvessels, ×100 (B). Immunohistochemical stain for CD31 of the same vessel showing many adventitial microvessels, ×100 (C). Haematoxylin and eosin stained vessel showing a small plaque in group 4, ×40 (D). Red arrowheads indicate immunohistochemical stain for VEGF of the same vessel showing many adventitial microvessels, ×100 (E). Immunohistochemical stain for CD31 of the same vessel showing many adventitial microvessels, ×100 (F). Haematoxylin and eosin stained vessel showing advanced plaque leading to lumen occlusion in group 5, ×40 (G). Immunohistochemical stain for VEGF of the same vessel showing numerous adventitial microvessels, ×100 (H). Immunohistochemical stain for CD31 of the same vessel showing numerous adventitial microvessels, ×100 (I). The red arrowheads in B, C, E, F, H and I indicate microvessels.

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