Figure 4
Circulating viremia of sertraline and placebo treated animals exposed to a lethal dose of Ebola virus. Animals were treated with 200 mg sertraline hydrochloride (red) or placebo (blue) by orogastric tube. Log10 plasma viremia levels as measured by plaque assay (a) and qRT-PCR (b) are shown as group means with SEM. Individual values are depicted as shapes. By day 6 post-exposure, animals exhibited substantial viremia that persisted until death. Statistical analysis showed no significant difference between placebo and sertraline treatment at D6.
