Figure 2 | Scientific Reports

Figure 2

From: Sudan ebolavirus long recovered survivors produce GP-specific Abs that are of the IgG1 subclass and preferentially bind FcγRI

Figure 2

Binding and activation of the reporters by sera from survivors of SUDV outbreak. Total IgG dependent activation through FcγRs with goat- anti human IgG. After pre-coating with goat-anti human IgG (2 µg/ml) the activation assay was performed (as described in the legend of Fig. 1) using a total of 14 non-infected and 14 survivors’ serum samples (including 5 serum samples from a longitudinal study for the GP-Gulu specificity). 1:1 K and 1:5 K sera dilution was used for BW-FcγRIIB response, and 1:5 K and 1:25 K for BW-FcγRIIIA/IIA/I response. mIL-2 secretion was determined by ELISA kit after 16 h incubation.

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