Figure 4

Immunohistochemical expression of COL1 and THBS2 in melanocytic tumors. (A) Cytoplasmic positivity for COL1 in numerous neoplastic cells and fewer stromal cells in a melanoma; (B) occasional COL1 positive cells in melanocytoma; (C) diffuse cytoplasmic stain for THBS2 in an amelanotic melanoma; (D) scattered and mild THBS2 positivity in melanocytoma cells.