Table 4 Antiviral activity against HSV-1 and cytotoxicity for compounds 1, 2, and 4 in Vero cellsa.

From: Rhodoterpenoids A‒C, Three New Rearranged Triterpenoids from Rhododendron latoucheae by HPLC‒MS‒SPE‒NMR

compound

TC50 b (μM)

IC50 (μM)

SIc

1

19.25

8.62

2.2

2

69.34

>33.33

—d

4

48.07

6.87

7.0

Acyclovire

>100

0.41

>243.9

  1. aData represent mean values for three independent determinations; bCytotoxic concentration required to inhibit Vero cell growth by 50%; cSelectivity index value equaled TC50/IC50; dThe selectivity index (SI) could not be determined under the test conditions; ePositive control.
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