Figure 2 | Scientific Reports

Figure 2

From: Evidence linking microRNA suppression of essential prosurvival genes with hippocampal cell death after traumatic brain injury

Figure 2

Ingenuity Pathway Analysis of TBI-induced miRNA target genes in dying vs surviving hippocampal neurons. miRNA-targeted genes are disproportionately represented in three prosurvival pathways, axon guidance, ERK/MAPK, and Ephrin receptor signaling. Prosurvival miRNA-target genes that are universally downregulated in the dying neurons are upregulated in surviving neurons (dashed lines connect the same region in dying pathway images with the enlarged surviving pathway images).

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