Figure 1 | Scientific Reports

Figure 1

From: Knockdown of anion exchanger 2 suppressed the growth of ovarian cancer cells via mTOR/p70S6K1 signaling

Figure 1

AE2 was up-regulated in human ovarian cancer tissues. (A) AE2 mRNA was over-expressed in ovarian cancer tissues compared to the normal tissues in TCGA dataset. Box-whiskers plot (Min to Max) was shown. (B) Genomic alterations of AE1 (SLC4A1), AE2 (SLC4A2) and AE3 (SLC4A3) in cBioportal ovarian cancer database. (C) mRNA expression of AE2 was examined by qPCR and normalized to GAPDH expression in 100 pairs of matched ovarian cancer tissues and adjacent non-tumorous tissue. Box-whiskers plot (Min to Max) was shown. (D) The protein levels of AE2 were higher in 10 pairs of matched samples of ovarian cancer tissue (T), compared with adjacent non-tumorous tissues (N). GAPDH was served as a loading control. (E) Kaplan–Meier survival analysis of 100 patients with ovarian cancer.

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