Figure 3 | Scientific Reports

Figure 3

From: Effects of 4(1H)-quinolinone derivative, a novel non-nucleotide allosteric purinergic P2Y 2 agonist, on cardiomyocytes in neonatal rats

Figure 3

Compound 89 allosterically potentiates ATP-induced changes in IEG gene expression in cardiomyocytes. Gene expression changes of IEGs, c-fos and the NR4A subfamily, in a time-dependent manner. Inductions by ATP (0, 1 or 10 μM) in the presence of Compound 89 (0, 10 or 30 μM) were plotted. Expression levels are normalized to Rplp0 and shown as means ± SEM (n = 3).

Back to article page