Table 2 Results of subgroup analysis.
Subgroup | No. of studies | HR (95% CI) | P value | Heterogeneity | |
|---|---|---|---|---|---|
I 2 | Ph | ||||
Overall survival | |||||
Sample size | |||||
>500 | 3 | 1.450 (1.100–1.913) | 0.008 | 36.3% | 0.208 |
≤500 | 13 | 3.284 (2.510–4.297) | <0.001 | 12.1% | 0.323 |
Study of region | |||||
Japan | 8 | 3.628 (2.344–5.615) | <0.001 | 53.7% | 0.034 |
others | 8 | 2.038 (1.402–2.963) | <0.001 | 50.3% | 0.050 |
Cut-off value of GPS | |||||
1 | 9 | 2.286 (1.533–3.409) | <0.001 | 61.9% | 0.007 |
2 | 7 | 3.506 (2.158–5.695) | <0.001 | 57.0% | 0.030 |
Cancer-specific survival | |||||
Sample size | |||||
>500 | 1 | 1.280 (1.084–1.512) | |||
≤500 | 10 | 2.098 (1.612–2.729) | <0.001 | 48.9% | 0.0728 |
Study of region | |||||
Asia | 9 | 2.29 (1.697–3.090) | <0.001 | 46.8% | 0.082 |
others | 2 | 1.315 (1.133–1.525) | <0.001 | 0% | <0.001 |
Cut-off value of GPS | |||||
1 | 5 | 1.589 (1.216–2.076) | 0.001 | 56.5% | 0.057 |
2 | 6 | 2.365 (1.599–3.500) | <0.001 | 48.5% | 0.084 |
