Figure 4

Inhibition of STAT3 reduced the expression of survivin and Ki-67 and induced apoptosis. (a) Representative views of the expression of p-STAT3, survivin and Ki-67 in S3I-201 treatment group and control group. (b) The expression levels of p-STAT3 and survivin were remarkably reduced after S3I-201 treatment,and their relative quantifications (c,d). *P < 0.05; ***P < 0.001.