Figure 6

Relationship between prevalence of 540E and 581G mutations when measured in the same individuals in (A) Eastern and Southern Africa (n = 172), (B) West Africa (n = 50), (C) Northeast Africa (n = 15) using surveys from 1988–2013. Mixed infections contribute to some of these measures, therefore the haplotype is unknown for most samples (i.e. the two mutations could be present together on one parasite or separately on different parasites). The sample size for assessing the prevalence of the two mutations was not always identical, usually due to different PCR success rates. Data in Eastern and Southern Africa were from the Democratic Republic of the Congo, Kenya, Mozambique, Malawi, Rwanda, Tanzania, Uganda, South Africa and Zambia; in West Africa from Angola, Benin, Burkina Faso, Côte d’Ivoire, Cameroon, Ghana, Equatorial Guinea, Mali, Mauritania, Niger and Senegal; and Northeast Africa from Ethiopia, Sudan and Somalia.