Figure 7 | Scientific Reports

Figure 7

From: MicroRNA-204 promotes vascular endoplasmic reticulum stress and endothelial dysfunction by targeting Sirtuin1

Figure 7

High-fat diet promotes vascular ER stress through miR-204. Immunoblots with quantification for BIP, p-PERK and ATF6 (A) and immunohistochemistry with quantification for BIP and CHOP (B) in aortas of C57Bl/6 mice fed a high-fat diet (HFD) and infused with miR-204 I or miR SC. Data is representative of three independent experiments and expressed relative to ND + miR SC. n = 3. *p < 0.05 vs ND + siRNA SC, ND + miR-204 I, and HFD + miR-204 I. #p < 0.05 vs ND + miR SC.

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