Figure 3 | Scientific Reports

Figure 3

From: Phenothiazines Enhance Mild Hypothermia-induced Neuroprotection via PI3K/Akt Regulation in Experimental Stroke

Figure 3

Neurological deficit (n = 7 per group) after combination therapy of mild hypothermia and C + P, using the 5-score system (a) and 12-score system (b). ANOVA analyses indicated that combination therapy (S&HD) significantly (**P < 0.01) reduced neurological deficits. Monotherapy with either mild hypothermia (S&H) or C + P (S&D) alone did not significantly improve outcomes in neuroprotection. Treatment with p-Akt inhibitor (LY294002) (S&HD&LY) reversed the combination therapy’s effect in neurological improvement (*P < 0.05).

Back to article page