Figure 7

Cx30 expression in cochlear outer sulcus and supra-strial zone of Cx30Δ/Δ mice four weeks after delivery of BAAVCx30GFP viral vector at P4. Shown are midmodiolar sections from injected Cx30Δ/Δ mice (Cx30Δ/Δ + BAAVCx30GFP) and non-injected wild type (WT) age-matched controls. Dashed arrows indicate gap junction plaques formed by recombinant Cx30GFP. The green signal was generated by immunostaining against GFP (Cx30Δ/Δ+ BAAVCx30GFP) and native Cx30 (WT), respectively. red, actin filaments; blue, nuclei. BC: Böttcher cells; CC: Claudius’ cells; DC: Deiters’ cells; RM: Reissners’ membrane; SP: spiral prominence; SSZ: supra-strial zone; SV: stria vascularis. Scale bars: 50 μm.