Figure 2

Magnetic resonance imaging on carotid arteries. (A) In vivo magnetic resonance imaging (MRI) and H&E staining from a C57BL/6 mouse subjected to wire injury in the left carotid artery. Following wire injury, the right carotid artery (control) appeared normal, whereas a blood clot obstructed the entire left (injured) carotid artery. (B) Correlation between MRI measurements and histological measurements of cross-sectional areas of injured carotid arteries. Values are averaged from 4 MRI cross-sections or 6–10 histological sections. n = 18. A statistically significant (p = 0.0045) correlation between MRI measured values and histology-derived values was found.