Figure 5
Wire injury, but not uremia, affects expression of smooth muscle marker genes in Apoe −/− mice. Real-time PCR analysis of carotid RNA (pooled two and two) from sham-operated (sham, n = 5) and uremic (NX, n = 10) Apoe −/− mice with (Injured) or without (Control) wire-induced vascular injury. Gene expression was normalized to CANX. Bars indicate mean ± SEM. 1-way ANOVA followed by Sidak’s multible comparison test, *p < 0.05, **p < 0.1, ***p < 0.001,****p < 0.0001. a.u.: arbitrary units. Acta2: Smooth muscle alpha actin; Myocd: Myocardin; Tagln: SM22 alpha; Myh11: Smooth muscle myosin heavy chain.
