Table 1 Values of Tm and ΔHm determined through thermal denaturation at pH 7.4 and protein size measured by dynamic light scattering.

From: A single amino acid substitution confers B-cell clonogenic activity to the HIV-1 matrix protein p17

 

refp17

S75X

p17R76G

Tm (°C)

62.82 ± 0.09

53.67 ± 0.15

52.83 ± 0.04

∆Hm (kcal/mol)

56.13 ± 0.91

63.80 ± 2.23

53.75 ± 0.43

Nominal molecular weight (Da)

15026

14864

14926

Particle molecular weight (Da)

16.2K

156K

27.8M

Granule diameter (nm)

4.06

10.7

98.5

Aggregation form

Monomer

Multimer

Multimer