Figure 1
From: Aggregated transthyretin is specifically packaged into placental nano-vesicles in preeclampsia
Transthyretin expression by preeclamptic placentae. Western blotting showed significantly higher levels of transthyretin in preeclamptic placentae compared to control placentae (*p = 0.0212, n = 7, A). Full-length blots are presented in Supplementary Figure 1. Immunofluorescent staining for transthyretin on placental sections from normotensive term (B) and preeclamptic pregnancies (C) showed higher levels of transthyretin in preeclamptic placentae. The granular staining of transthyretin are arrowed and can be seen most clearly in the control. Quantitative RT-PCR suggests that the mRNA levels of transthyretin were not different between preeclamptic and control placental explants (n = 8, D). Mean and SEM are depicted.
