Table 2 Results of the analysis of variance for different melatonin variables. In bold results with p < 0.05.

From: Differential impact in young and older individuals of blue-enriched white light on circadian physiology and alertness during sustained wakefulness

Variable

Mean ± standard error of the mean

Analysis of variance

DL (Young/Older)

WL (Young/Older)

BL (Young/Older)

Light

Age

Light*Age

Mel-on (h:min ± h:min)

21:48 ± 00:12/22:10 ± 00:10

22:58 ± 00:11/22:54 ± 00:26

23:08 ± 00:20/22:40 ± 00:24

F 2,58.7  = 17.1, p < 0.0001

F1, 35.4 = 0.0, p = 0.9801

F2,58.7 = 1.5, p = 0.2417

Mel-off (h:min ± h:min)

07:55 ± 00:15/07:53 ± 00:25

07:52 ± 00:15/07:42 ± 00:28

07:42 ± 00:10/07:42 ± 00:13

F2,60 = 0.3 p = 0.7377

F1,35.1 = 0.3, p = 0.8647

F2,60 = 0.0, p = 0.9917

Midpoint (h:min ± h:min)

02:50 ± 00:13/03:01 ± 00:18

03:25 ± 00:11/03:17 ± 00:20

03:25 ± 00:12/03:11 ± 00:15

F 2,58.1  = 4.9, P = 0.0107

F1,35.3 = 0.0, p = 0.9469

F2,58.1 = 0.7, p = 0.5221

Amplitude (pg/ml)

17.23 ± 1.83/11.87 ± 2.07

14.29 ± 1.86/11.48 ± 2.40

12.32 ± 1.77/11.83 ± 2.09

F2,57.5 = 2.0, p = 0.1446

F1,35 = 1.4, p = 0.2505

F2,57.5 = 1.6, p = 0.2079

AUC (ng-hours/L)

5.47 ± 0.59/3.74 ± 0.65

4.04 ± 0.57/3.10 ± 0.68

3.25 ± 0.46/3.33 ± 0.62

F 2,57  = 8.5, p = 0.0006

F1,34.8 = 1.4, p = 0.2475

F2,57 = 2.4, p = 0.0974

COG (h:min ± h:min)

02:38 ± 00:13/02:56 ± 00:20

03:22 ± 00:12/03:17 ± 00:19

03:27 ± 00:12/03:11 ± 00:20

F 2,58  = 9.2, p = 0.0003

F1,35.3 = 0.0, p = 0.9726

F2,58 = 1.5, p = 0.2416

  1. Mel-on: Melatonin onset; Mel-off: Melatonin offset; AUC: Area Under the Curve; COG: Centre Of Gravity of the fitted melatonin curve.
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