Figure 7

ZIKV infection in AIR mice does not cause extensive placental barrier breakdown. (A,B) Gross histological analysis of Evans Blue dye leakage across the placenta into the umbilical cord and fetuses of embryonic day 17–18 ZIKV-infected AIR mice. (C,D) Non-Evans Blue injected control fetuses from the same embryonic day. (E) IHC sections labeled for ZIKV NS5 protein (green), Sox2 (magenta) and DAPI (blue) from the neocortical ventricular zone of the fetus shown in (A).