Figure 5
From: Characterisation of lung macrophage subpopulations in COPD patients and controls
The diameter of alveolar and interstitial macrophages in lung resected tissue. Alveolar (AM) and interstitial (IM) macrophages from never smokers (NS) (n = 11) (A), smoking controls (S) (n = 15) (B) and COPD patients (COPD) (n = 12) (C) were identified in FFPE resected lung tissue by co-expression of CX3CR1 and CD14 and the diameter of each cell was measured. Data are shown as the percentage of macrophage population measuring a certain diameter (A-C) or individual cell diameters for IMs (D) and AMs (E) with median and interquartile range. Mann-whitney t-tests were performed between IM and AMs. One way ANOVA followed by Tukey-Kramer Multiple Comparisons Test were performed between subject groups. **,***Significant difference (p < 0.01, < 0.001 respectively)
