Figure 5
From: Quantitative Proteomics of Cerebrospinal Fluid in Paediatric Pneumococcal Meningitis
Label-free quantification of confidently identified and quantified proteins. Whiskers indicate the 95% and 5% boundaries of the data and the horizontal bar within the box is the median. Control samples are blue and SPP are red. Yellow shading is used to highlight the two proteins present at lower levels in SPP. Proteins are defined by their UniProtKB ID P01024: Complement C3, P01023: Alpha-2-macroglobulin, P0C0L4: Complement C4-A, P02788: Lactotransferrin, P01009: Alpha-1-antitrypsin, P00738: Haptoglobin, P02671: Fibrinogen alpha-chain, P00450: Ceruloplasmin, P04114: Apolipoprotein B-100, P02675: Fibrinogen beta chain, P05164: Myeloperoxidase, Q92520: Protein FAM3C, P01034: Cystatin-C. Probabilities were calculated using the t-test function in R and corrected for multiple testing by Benjamini and Hochberg method. Corrected p-values are shown in the panels. Individual data points are shown for controls (n = 12) and SPP (n = 16) samples.
