Figure 4 | Scientific Reports

Figure 4

From: A cancer stem cell model as the point of origin of cancer-associated fibroblasts in tumor microenvironment

Figure 4

Characterization of differentiating CAFLCs and histochemistry. (a) RT-qPCR analysis of the CAF markers FSP1, vimentin, TGFβ1, CXCL12, and PDGFα in CSCcmBT549-CAFLCs. The data were analyzed using an unpaired two-tailed Student’s t-test and are presented as the mean ± standard deviation. ***P < 0.001, **P < 0.01, *P < 0.05. (b) Hematoxylin-eosin staining of subcutaneous tumors generated from CSCcmT47D and CSCcmBT549 spheres. Scale bars represent 200 μm.

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