Figure 2 | Scientific Reports

Figure 2

From: Intestinal toxicity of the type B trichothecene mycotoxin fusarenon-X: whole transcriptome profiling reveals new signaling pathways

Figure 2

Effect of exposure of the jejunal explants to different levels of DON or FX. Top panel: Morphological scores (black) and lesional scores (striped) observed following the 4-hour exposure to DON or FX. The values are the mean percentage ± SD. a,bMean values with different letters were significantly different (p < 0.05). Tukey test. Bottom panel: Histological aspects. (a) Control explant. Villi lined with columnar enterocytes (HE, 20x); (b) 3 µM DON-exposed explant. Moderate fusion (black arrow) and villi showing cubic epithelial cells (dotted arrow) (HE, 20x); (c) 3 µM FX-exposed explant. Villi showing severe apical necrosis (red arrow) and diffuse cellular debris (*) (HE, 20x).

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