Table 1 Benchmark doses for the intestinal up-regulation of the NF-κB transcription factor and pro-inflammatory cytokine gene expression by FX.

From: Intestinal toxicity of the type B trichothecene mycotoxin fusarenon-X: whole transcriptome profiling reveals new signaling pathways

Genes

BMD (µM)

BMDL (µM)

NF-κB

0.73

0.34

TNF-α

0.57

0.34

TNFAIP3

0.3

0.07

CXCL-2

0.13

0.05

CSF2

0.18

0.07

IL-1β

0.14

0.04

IL-8

0.14

0.08

IL-17A

0.15

0.05

IL-22

0.5

0.33