Table 1 Benchmark doses for the intestinal up-regulation of the NF-κB transcription factor and pro-inflammatory cytokine gene expression by FX.
Genes | BMD (µM) | BMDL (µM) |
---|---|---|
NF-κB | 0.73 | 0.34 |
TNF-α | 0.57 | 0.34 |
TNFAIP3 | 0.3 | 0.07 |
CXCL-2 | 0.13 | 0.05 |
CSF2 | 0.18 | 0.07 |
IL-1β | 0.14 | 0.04 |
IL-8 | 0.14 | 0.08 |
IL-17A | 0.15 | 0.05 |
IL-22 | 0.5 | 0.33 |