Figure 4
From: Structure of the C-terminal domain of TRADD reveals a novel fold in the death domain superfamily
Interaction between TRADD DD and p75NTR DD. (A) Expanded region of [1H-15N] HSQC spectra of p75NTR DD in the absence (black) and presence (red) of TRADD DD at 28 °C in water. The concentration of TRADD DD is ~0.3 mM and the molar ratio of TRADD DD to p75NTR DD is ~1:2. Perturbed residues are labelled. (B) Surface presentation of p75NTR DD homodimer. p75NTR DD homo-dimerization interface is indicated by an arrow. Most-perturbed residues on the structural region of p75NTR DD are colored in red and circled in blue. *Cross peaks from the N-/C-terminal tails.
