Figure 2 | Scientific Reports

Figure 2

From: Thermoneutral housing temperature regulates T-regulatory cell function and inhibits ovabumin-induced asthma development in mice

Figure 2

The effects of ambient temperature on IFN-γ, IL-4, IL-13 and serum OVA specific IgE. The BALF and sera were collected from the mice and analyzed by ELISA. The bars indicate the cytokine levels in the BALF (A) and the antigen-specific IgE in the serum (B). ST: standard temperature (20 °C); TT: thermoneutral temperature (30 °C). Control: Naïve mice. Asthma: Asthma mice. (C) Spleen cells were cultured at the indicated temperature for 48 h in the presence of ionomycin. The data are presented as mean ± SEM. *P < 0.01 (t test). Each group consists of 6 mice.

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