Table 1 Histopathological scoring of inflammatory change in the lungs of mice.

From: Thermoneutral housing temperature regulates T-regulatory cell function and inhibits ovabumin-induced asthma development in mice

 

ST-control

ST-asthma

TT-control

TT-asthma

Peribronchiolar eosinophilia

0.33 ± 0.52*

3.16 ± 0.75

0.16 ± 0.40*

2.11 ± 0.63#

Perivascular eosinophilia

0.16 ± 0.40*

1.83 ± 0.75

0.33 ± 0.82*

1.33 ± 0.52

Oedema

0.33 ± 0.52*

3.52 ± 0.55

0.16 ± 0.40*

1.83 ± 0.75#

Epithelial damage

0.16 ± 0.40*

3.51 ± 1.05

0.33 ± 0.82*

3.01 ± 0.89

  1. Inflammatory changes were graded by histopathological assessment using a semiquantitative scale of 0–5 (Table 2). ST: standard temperature (20 °C); TT: thermoneutral temperature (30 °C). The data presented are mean ± SEM. * denotes P < 0.05 (ST-control vs. ST-asthma or TT-control vs.TT-asthma); #denotes P < 0.05 (TT-asthma vs. ST-asthma) (n = 6 mice per group).
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