Figure 1 | Scientific Reports

Figure 1

From: Lipoxin A4 and its analog suppress inflammation by modulating HMGB1 translocation and expression in psoriasis

Figure 1

BML-111 improves the morphological and histological features of IMQ-induced psoriasiform dermatitis in mice. (A) Schematic representation of the animal experiment protocol. (B) Representative macroscopic views of the dorsal skin of BALB/c mice following continuous treatment for 8 days. (C) Epidermal erythema, scaling and thickening of the dorsal skin were evaluated daily; the clinical PASI score was calculated by adding the scores of the three separate criteria (range from 0 to 12). (D) HE staining of cross-sectional slices from the dorsal skin of the three groups of mice. (E) Epidermal thickness of the dorsal skin on day 8. **p < 0.01 and *p < 0.05, compared with the mice in the IMQ group. Each bar represents the mean ± SD (n = 8).

Back to article page