Figure 6 | Scientific Reports

Figure 6

From: RNA SEQ Analysis Indicates that the AE3 Cl−/HCO3 − Exchanger Contributes to Active Transport-Mediated CO2 Disposal in Heart

Figure 6

Differential expression of genes with potential for adaptation via Na+-loading or regulation of pHi. Genes in the top row have the potential to contribute to increased contractility via regulation of Na+-loading. Genes in the second row are affected by or involved in intracellular acid-base homeostasis. RPKM values for WT (black bars) and AE3-null (white bars) hearts are shown. Values are means ± SE; n = 4 for each genotype; *p ≤ 0.01 vs WT controls, except Car14 (p = 0.019), which encodes CA XIV, an AE3-interacting protein.

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