Figure 6

Endophilin B2 shapes inflammatory cell recruitment and suppresses recovery of AMs after IAV infection. The number of neutrophils, Ly-6C + monocytes, and AMs in lungs (A, C, E) and BAL (B, D, F), respectively, was determined by flow cytometry. Significant differences in the number of cell types between WT and B2−/− mice were calculated for (A) *p < 0.02 at day 12, (B) *p < 0.01 at day 3, (D) *p < 0.0002 at day 12, (E) *p < 0.007 at day 3, and (F) *p < 0.02 at day 12. (n = 3 mice per group at t = 0, 3, and 7, and n = 12 at t = 12. The data on day 12 are pooled from three independent experiments.)