Figure 9 | Scientific Reports

Figure 9

From: SH3GLB2/endophilin B2 regulates lung homeostasis and recovery from severe influenza A virus infection

Figure 9

Endophilin B2 uncouples the temporal expression of CEBP transcription factors in IAV infected lugs. The expression of (A) Cebpd, (B) Cebpb, and (C) Cebpa mRNA were quantitated by qRT-PCR in total lung. Data were normalized to 18 S RNA and expressed as relative quantity (RQ) compared to WT uninfected control treated with DPBS vehicle. ***p < 0.00001, **p < 0.007, *p < 0.02 (for WT n = 4, 9, 8, and 6 and B2−/− n = 3, 7, 8, and 6 at t = 0, 3, 7, and 14 days; the vehicle treated mice are plotted as t = 0. Data ± SEM are from 2 independent experiments).

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