Table 1 The risk allele frequency of acute coronary syndrome patients in three outcome.

From: Effect of carboxylesterase 1 S75N on clopidogrel therapy among acute coronary syndrome patients

Clinical outcomes

Occurrence (N = 851)

N§(CC vs CT + TT) (N = 471 vs 374)

RAF

P*

ORϮ (95CI)

Cerebrovascular event

YES (N = 84)

66 vs 18

0.11

1.521 × 10−4

0.39 (0.24–0.65)

NO (N = 767)

405 vs 356

0.24

Acute myocardial infarction

YES (N = 94)

71 vs 23

0.12

4.619 × 10−4

0.45 (0.29–0.71)

NO (N = 757)

400 vs 351

0.24

Unstable angina

YES (N = 439)

296 vs 141

0.16

3.948 × 10−10

0.48 (0.38–0.6)

NO (N = 412)

175 vs 233

0.29

  1. §Numbers of CC genotype patients vs CT + TT genotype patients who occurred endpoints.
  2. *The P value has been adjusted; CI = confidence interval; OR = odds ratio; RAF = risk allele frequency.
  3. ϮOdds ratio represents the increase in the risk of happening endpoints for each copy of the risk allele compared with subjects who do not carry the risk allele. P values and odds ratios were estimated by PLINK.
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