Table 2 Clinical characteristics in the CES1 S75N genotype groups in all subjects.

From: Effect of carboxylesterase 1 S75N on clopidogrel therapy among acute coronary syndrome patients

 

CC (N = 471)

CT + TT (N = 374)

P value

Clinical characteristics

 Age (years)

62.86 ± 11.42

63.93 ± 11.87

0.185

 Males

334 (70.9)

270 (72.2)

0.370

 Smoking

224 (47.9)

181 (48.7)

0.437

 Hypertension

345 (73.2)

240 (64.2)

0.003

 Stent

401 (85.1)

290 (77.5)

0.003

 Diabetes

159 (33.8)

108 (28.9)

0.075

 Hyperlipemia

289 (61.4)

131 (35)

<0.001

 CCB

235 (50.1)

161 (43.2)

0.026

 PPI

86 (18.3)

126 (33.8)

<0.001

Clinical outcomes

 Cerebrovascular event

66 (14)

18 (4.8)

<0.001

 Acute myocardial infarction

71 (15.1)

23 (6.1)

<0.001

 Unstable angina

296 (62.8)

141 (37.7)

<0.001

  1. Measure data are N (%), continuous data are mean ± standard deviation (SD), unless otherwise indicated.