Table 2 Clinical characteristics in the CES1 S75N genotype groups in all subjects.
From: Effect of carboxylesterase 1 S75N on clopidogrel therapy among acute coronary syndrome patients
CC (N = 471) | CT + TT (N = 374) | P value | |
---|---|---|---|
Clinical characteristics | |||
Age (years) | 62.86 ± 11.42 | 63.93 ± 11.87 | 0.185 |
Males | 334 (70.9) | 270 (72.2) | 0.370 |
Smoking | 224 (47.9) | 181 (48.7) | 0.437 |
Hypertension | 345 (73.2) | 240 (64.2) | 0.003 |
Stent | 401 (85.1) | 290 (77.5) | 0.003 |
Diabetes | 159 (33.8) | 108 (28.9) | 0.075 |
Hyperlipemia | 289 (61.4) | 131 (35) | <0.001 |
CCB | 235 (50.1) | 161 (43.2) | 0.026 |
PPI | 86 (18.3) | 126 (33.8) | <0.001 |
Clinical outcomes | |||
Cerebrovascular event | 66 (14) | 18 (4.8) | <0.001 |
Acute myocardial infarction | 71 (15.1) | 23 (6.1) | <0.001 |
Unstable angina | 296 (62.8) | 141 (37.7) | <0.001 |