Figure 2 | Scientific Reports

Figure 2

From: Age-dependent motor dysfunction due to neuron-specific disruption of stress-activated protein kinase MKK7

Figure 2

Analysis of brain size. (a) Gross appearance of control and MKK7 cKO mouse brain at 4 months-old. (b) Brain wet weights of control and MKK7 cKO mice between 1–12 weeks-old. (c) Brain volumes of 8 month-old control and MKK7 cKO mice. Volumes were calculated from contiguous slice images acquired by CT scan. (d) Immunostaining of cortical neurons. Sections were prepared from 3 month-old control and MKK7 cKO mice and stained with anti-NeuN antibody. (e) Numbers of NeuN positive cells per section. (f-h) Coronal sections were prepared from 3 month-old control and MKK7 cKO brains. (g) Thickness of cortex. (h) Relative areas of white matter. CC: Corpus Callosum, AC: Anterior commissure. *p < 0.05.

Back to article page