Figure 5 | Scientific Reports

Figure 5

From: Age-dependent motor dysfunction due to neuron-specific disruption of stress-activated protein kinase MKK7

Figure 5

Analysis of muscle and spinal cord. (a) Dissected gastrocnemius muscles from MKK7 cKO and control mice at the indicated ages. (b) Immunostaining of ChAT positive motor neurons in spinal cord. LSC were collected from 9 month-old MKK7 cKO and control mice. Scale bar, 100 μm. (c) Averaged numbers of ChAT positive cells per section. Ctrl: n = 4; MKK7 cKO: n = 5. (d) Toluidine blue staining of semi-thin sections of LSC. LSC were collected from 9 month-old MKK7 cKO and control mice. Arrowheads indicate degenerating axons. Left panels, scale bar indicates 250 μm. Middle panels are areas magnified from the left panels. Scale bar, 50 μm. Right panels are magnified from the middle panels. Scale bar, 10 μm.

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