Figure 6 | Scientific Reports

Figure 6

From: Age-dependent motor dysfunction due to neuron-specific disruption of stress-activated protein kinase MKK7

Figure 6

Analysis of APP and JIP1 protein levels in nervous tissues. (a) cDNA microarray and hierarchical cluster analysis of MKK7 cKO mice brain. Heat map showing expression patterns of 8 month-old MKK7 cKO and control brain. (b) Immunoblotting of APP and JIP1 in spinal cord. Extracts of spinal cord from 3 month-old MKK7 cKO and control mice were used. β3-tublin and actin are loading controls. (c and d) Immunoblotting of APP both in the spinal cord and brain. Extracts of brain and spinal cord were prepared from MKK7 cKO and control mice at the indicated ages. GAPDH is the loading control.

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