Figure 1 | Scientific Reports

Figure 1

From: Up-regulation of BRCA1-associated RING Domain 1 Promotes Hepatocellular Carcinoma Progression by Targeting Akt Signaling

Figure 1

BARD1 mRNA up-regulation in HCC and the relationship with patient survival. (A) qRT-PCR analysis of BARD1 was carried out in 209 paired HCC and matched ANLT. For each sample, the relative expression level of BARD1 was normalized based on that of the internal reference β-actin, the line within each box represents the median −ΔCt value. (B) The distribution of both BARD1 mRNA expression and serum AFP levels in 209 HCC patients; the numbers in the pie indicate the percentages of BARD1 and/or AFP whose level is high or low in HCC specimens. Patients with high BARD1 expression profile had a poorer outcome for both PFS (C) and OS (D) among the HCC patients.

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