Table 1 Correlation between the clinicopathologic variables and BARD1 in HCC.
Clinical character | Clinical variable | No. of patients | BARD1 mRNA | χ2 | P value | |
|---|---|---|---|---|---|---|
low n (%) | high n (%) | |||||
Gender | Female | 33 | 7 (21.2) | 26 (78.8) | 1.485 | 0.223 |
Male | 176 | 56 (31.8) | 120 (68.2) | |||
Age (years) | ≤55 | 141 | 39 (27.7) | 102 (72.3) | 1.270 | 0.260 |
>55 | 68 | 24 (35.3) | 44 (64.7) | |||
Family history | No | 176 | 51 (29.0) | 125 (71.0) | 0.720 | 0.396 |
Yes | 33 | 12 (36.4) | 21 (63.6) | |||
HBsAg | Negative | 39 | 19 (48.7) | 20 (51.3) | 7.856 | 0.005 |
Positive | 170 | 44 (25.9) | 126 (74.1) | |||
Median size (range, cm) | ≤5 | 73 | 31 (42.5) | 42 (57.5) | 8.089 | 0.004 |
>5 | 136 | 32 (23.5) | 104 (76.5) | |||
Cirrhosis | No | 20 | 3 (15.0) | 17 (85.0) | 2.409 | 0.121 |
Yes | 189 | 60 (31.7) | 129 (68.3) | |||
Tumor number | Single | 141 | 46 (32.6) | 95 (67.4) | 1.266 | 0.260 |
Multiple | 68 | 17 (25.0) | 51 (75.0) | |||
Wine-drinking | No | 103 | 32 (31.1) | 71 (68.9) | 0.082 | 0.774 |
Yes | 106 | 31 (29.2) | 75 (70.8) | |||
TNM stage | I–II | 91 | 39 (42.9) | 52 (57.1) | 12.372 | <0.001 |
III–IV | 118 | 24 (20.3) | 94 (79.7) | |||
Metastasis | No | 178 | 55 (30.9) | 123 (69.1) | 0.325 | 0.569 |
Yes | 31 | 8 (25.8) | 23 (74.2) | |||
BCLC stage | 0-A | 96 | 38 (39.6) | 58 (60.4) | 7.514 | 0.006 |
B–C | 113 | 25 (22.1) | 88 (77.9) | |||
AFP (ng/mL) | ≤100 | 84 | 34 (40.5) | 50 (59.5) | 7.121 | 0.008 |
>100 | 125 | 29 (23.2) | 96 (76.8) | |||
AST (U/L) | ≤40 | 97 | 39 (40.2) | 58 (59.8) | 8.704 | 0.003 |
>40 | 112 | 24 (21.4) | 88 (78.6) | |||
Recurrence | No | 135 | 39 (28.9) | 96 (71.1) | 0.285 | 0.593 |
Yes | 74 | 24 (32.4) | 50 (67.6) | |||
