Table 3 The important up regulation genes of JS32 compared to JS0135 grouped by GO and KEGG pathways of interest.

From: Comparative transcriptional profiling of tildipirosin-resistant and sensitive Haemophilus parasuis

Gene

Product description

P-value

Fold change

Metabolic pathways

HAPS_RS09315

restriction endonuclease subunit M

7.70E-301

Inf

HAPS_RS09320

DNA cytosine methyltransferase

0.00E + 00

Inf

HAPS_RS06285

phosphate acyltransferase

4.48E-19

3.40

HAPS_RS11130

phosphatidylglycerophosphatase A

8.85E-04

4.62

HAPS_RS06145

phosphatidate cytidylyltransferase

1.50E-08

2.24

HAPS_RS06125

phosphatidylglycerophosphatase

7.41E-05

2.04

glmM

phosphoglucosamine mutase

2.77E-11

2.60

HAPS_RS04930

beta-hexosaminidase

7.43E-17

4.02

HAPS_RS03600

UDP-N-acetylglucosamine 1-carboxyvinyltransferase

7.78E-06

2.09

HAPS_RS08950

thiamine phosphate synthase

1.46E-11

Inf

HAPS_RS08955

hydroxymethylpyrimidine/phosphomethylpyrimidine kinase

3.06E-12

Inf

HAPS_RS07450

myo-inosose-2 dehydratase

2.38E-37

6.39

HAPS_RS07445

3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing)

1.83E-56

19.75

HAPS_RS04065

phosphogluconate dehydrogenase

2.69E-06

2.03

ilvH

acetolactate synthase small subunit

5.98E-03

2.35

HAPS_RS00040

fumarate reductase

6.68E-05

2.83

apaH

bis(5\-nucleosyl)-tetraphosphatase (symmetrical)

1.77E-04

2.01

HAPS_RS05675

anaerobic ribonucleoside-triphosphate reductase

1.20E-07

2.19

HAPS_RS09780

guanylate kinase

6.10E-04

2.21

dnaE

DNA polymerase III subunit alpha

1.15E-06

2.21

HAPS_RS01460

IMP dehydrogenase

9.93E-08

2.18

HAPS_RS09615

phosphoribosylformylglycinamidine synthase

1.18E-13

2.85

HAPS_RS07125

xanthine phosphoribosyltransferase

1.44E-07

6.35

HAPS_RS05080

PLP-dependent threonine dehydratase

1.64E-11

2.56

HAPS_RS08960

hydroxyethylthiazole kinase

1.22E-06

Inf

HAPS_RS09895

dihydroorotate dehydrogenase 2

1.14E-06

2.53

HAPS_RS06125

phosphatidylglycerophosphatase

7.41E-05

2.04

HAPS_RS04950

lipooligosaccharide D-glycero-D-manno-heptosyltransferase

3.14E-09

2.50

upp

uracil phosphoribosyltransferase

6.72E-16

3.23

HAPS_RS07455

inositol 2-dehydrogenase

3.73E-08

2.38

HAPS_RS07450

myo-inosose-2 dehydratase

2.38E-37

6.39

Ribosome

HAPS_RS07815

MULTISPECIES: 50S ribosomal protein L16

4.98E-31

4.46

HAPS_RS07810

30S ribosomal protein S3

3.93E-23

3.80

HAPS_RS07825

30S ribosomal protein S17

2.24E-11

2.64

HAPS_RS07790

MULTISPECIES: 50S ribosomal protein L23

1.46E-21

3.44

rpsJ

MULTISPECIES: 30S ribosomal protein S10

7.68E-16

2.99

HAPS_RS07805

MULTISPECIES: 50S ribosomal protein L22

2.57E-23

3.71

HAPS_RS07795

50S ribosomal protein L2

6.51E-16

3.31

HAPS_RS07780

50S ribosomal protein L3

6.11E-17

3.20

rplD

50S ribosomal protein L4

5.49E-21

3.67

HAPS_RS07800

MULTISPECIES: 30S ribosomal protein S19

1.91E-18

3.43

HAPS_RS07820

MULTISPECIES: 50S ribosomal protein L29

8.16E-16

3.19

ABC transporters

HAPS_RS10945

phosphonate ABC transporter permease

1.30E-02

2.51

HAPS_RS03625

ABC transporter permease

1.43E-05

2.35

HAPS_RS05335

membrane protein

0.02

3.03

HAPS_RS05330

manganese transporter

0.02

2.20

HAPS_RS03630

ABC transporter ATP-binding protein

6.61E-05

2.30

HAPS_RS00315

hypothetical protein

6.26E-03

3.41

HAPS_RS01125

cysteine/glutathione ABC transporter ATP-binding protein/permease CydC

1.43E-13

2.88

HAPS_RS04845

ABC transporter substrate-binding protein

1.50E-07

2.13

HAPS_RS00310

ABC transporter family protein

3.07E-03

2.62

HAPS_RS05165

arginine transporter permease subunit ArtQ

1.18E-02

2.05

HAPS_RS04855

peptide ABC transporter permease

3.44E-05

2.03

CAMP resistance

HAPS_RS07240

hypothetical protein

4.61E-03

2.69

HAPS_RS11325

calcium-binding domain-containing protein

2.25E-04

2.06

HAPS_RS06175

acyl

4.96E-07

2.07

  1. Note: Inf, represented infinity.