Table 3 The important up regulation genes of JS32 compared to JS0135 grouped by GO and KEGG pathways of interest.
From: Comparative transcriptional profiling of tildipirosin-resistant and sensitive Haemophilus parasuis
Gene | Product description | P-value | Fold change |
---|---|---|---|
Metabolic pathways | |||
HAPS_RS09315 | restriction endonuclease subunit M | 7.70E-301 | Inf |
HAPS_RS09320 | DNA cytosine methyltransferase | 0.00E + 00 | Inf |
HAPS_RS06285 | phosphate acyltransferase | 4.48E-19 | 3.40 |
HAPS_RS11130 | phosphatidylglycerophosphatase A | 8.85E-04 | 4.62 |
HAPS_RS06145 | phosphatidate cytidylyltransferase | 1.50E-08 | 2.24 |
HAPS_RS06125 | phosphatidylglycerophosphatase | 7.41E-05 | 2.04 |
glmM | phosphoglucosamine mutase | 2.77E-11 | 2.60 |
HAPS_RS04930 | beta-hexosaminidase | 7.43E-17 | 4.02 |
HAPS_RS03600 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | 7.78E-06 | 2.09 |
HAPS_RS08950 | thiamine phosphate synthase | 1.46E-11 | Inf |
HAPS_RS08955 | hydroxymethylpyrimidine/phosphomethylpyrimidine kinase | 3.06E-12 | Inf |
HAPS_RS07450 | myo-inosose-2 dehydratase | 2.38E-37 | 6.39 |
HAPS_RS07445 | 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing) | 1.83E-56 | 19.75 |
HAPS_RS04065 | phosphogluconate dehydrogenase | 2.69E-06 | 2.03 |
ilvH | acetolactate synthase small subunit | 5.98E-03 | 2.35 |
HAPS_RS00040 | fumarate reductase | 6.68E-05 | 2.83 |
apaH | bis(5\-nucleosyl)-tetraphosphatase (symmetrical) | 1.77E-04 | 2.01 |
HAPS_RS05675 | anaerobic ribonucleoside-triphosphate reductase | 1.20E-07 | 2.19 |
HAPS_RS09780 | guanylate kinase | 6.10E-04 | 2.21 |
dnaE | DNA polymerase III subunit alpha | 1.15E-06 | 2.21 |
HAPS_RS01460 | IMP dehydrogenase | 9.93E-08 | 2.18 |
HAPS_RS09615 | phosphoribosylformylglycinamidine synthase | 1.18E-13 | 2.85 |
HAPS_RS07125 | xanthine phosphoribosyltransferase | 1.44E-07 | 6.35 |
HAPS_RS05080 | PLP-dependent threonine dehydratase | 1.64E-11 | 2.56 |
HAPS_RS08960 | hydroxyethylthiazole kinase | 1.22E-06 | Inf |
HAPS_RS09895 | dihydroorotate dehydrogenase 2 | 1.14E-06 | 2.53 |
HAPS_RS06125 | phosphatidylglycerophosphatase | 7.41E-05 | 2.04 |
HAPS_RS04950 | lipooligosaccharide D-glycero-D-manno-heptosyltransferase | 3.14E-09 | 2.50 |
upp | uracil phosphoribosyltransferase | 6.72E-16 | 3.23 |
HAPS_RS07455 | inositol 2-dehydrogenase | 3.73E-08 | 2.38 |
HAPS_RS07450 | myo-inosose-2 dehydratase | 2.38E-37 | 6.39 |
Ribosome | |||
HAPS_RS07815 | MULTISPECIES: 50S ribosomal protein L16 | 4.98E-31 | 4.46 |
HAPS_RS07810 | 30S ribosomal protein S3 | 3.93E-23 | 3.80 |
HAPS_RS07825 | 30S ribosomal protein S17 | 2.24E-11 | 2.64 |
HAPS_RS07790 | MULTISPECIES: 50S ribosomal protein L23 | 1.46E-21 | 3.44 |
rpsJ | MULTISPECIES: 30S ribosomal protein S10 | 7.68E-16 | 2.99 |
HAPS_RS07805 | MULTISPECIES: 50S ribosomal protein L22 | 2.57E-23 | 3.71 |
HAPS_RS07795 | 50S ribosomal protein L2 | 6.51E-16 | 3.31 |
HAPS_RS07780 | 50S ribosomal protein L3 | 6.11E-17 | 3.20 |
rplD | 50S ribosomal protein L4 | 5.49E-21 | 3.67 |
HAPS_RS07800 | MULTISPECIES: 30S ribosomal protein S19 | 1.91E-18 | 3.43 |
HAPS_RS07820 | MULTISPECIES: 50S ribosomal protein L29 | 8.16E-16 | 3.19 |
ABC transporters | |||
HAPS_RS10945 | phosphonate ABC transporter permease | 1.30E-02 | 2.51 |
HAPS_RS03625 | ABC transporter permease | 1.43E-05 | 2.35 |
HAPS_RS05335 | membrane protein | 0.02 | 3.03 |
HAPS_RS05330 | manganese transporter | 0.02 | 2.20 |
HAPS_RS03630 | ABC transporter ATP-binding protein | 6.61E-05 | 2.30 |
HAPS_RS00315 | hypothetical protein | 6.26E-03 | 3.41 |
HAPS_RS01125 | cysteine/glutathione ABC transporter ATP-binding protein/permease CydC | 1.43E-13 | 2.88 |
HAPS_RS04845 | ABC transporter substrate-binding protein | 1.50E-07 | 2.13 |
HAPS_RS00310 | ABC transporter family protein | 3.07E-03 | 2.62 |
HAPS_RS05165 | arginine transporter permease subunit ArtQ | 1.18E-02 | 2.05 |
HAPS_RS04855 | peptide ABC transporter permease | 3.44E-05 | 2.03 |
CAMP resistance | |||
HAPS_RS07240 | hypothetical protein | 4.61E-03 | 2.69 |
HAPS_RS11325 | calcium-binding domain-containing protein | 2.25E-04 | 2.06 |
HAPS_RS06175 | acyl | 4.96E-07 | 2.07 |