Table 4 The important down regulation genes of JS32 compared to JS0135 grouped by GO and KEGG pathways of interest.
From: Comparative transcriptional profiling of tildipirosin-resistant and sensitive Haemophilus parasuis
Gene/Pathway | Product description | P-value | Fold change |
|---|---|---|---|
Phosphotransferase system (PTS) | |||
HAPS_RS00970 | PTS mannose transporter subunit IIAB | 1.11E-65 | 0.16 |
HAPS_RS04655 | PTS glucose transporter subunit IIA | 6.63E-15 | 0.39 |
HAPS_RS04905 | PTS sucrose transporter subunit IIBC | 8.57E-38 | 0.17 |
HAPS_RS06060 | hypothetical protein | 5.60E-18 | 0.34 |
HAPS_RS00960 | PTS fructose transporter subunit IID | 7.69E-51 | 0.16 |
HAPS_RS00965 | PTS fructose transporter subunit IIC | 6.71E-50 | 0.20 |
Metabolic pathways | |||
HAPS_RS07375 | glycerol-3-phosphate acyltransferase | 4.07E-19 | 0.40 |
HAPS_RS09985 | galactose-1-phosphate uridylyltransferase | 3.50E-16 | 0.43 |
HAPS_RS00955 | beta-galactosidase | 1.84E-28 | 0.38 |
HAPS_RS05910 | N-acetylmannosamine-6-phosphate 2-epimerase | 3.35E-17 | 0.43 |
HAPS_RS06560 | 5-methyltetrahydropteroyltriglutamate–homocysteine S-methyltransferase | 1.02E-20 | 0.35 |
HAPS_RS02470 | S-adenosylmethionine synthase | 1.84E-21 | 0.42 |
HAPS_RS10200 | glutamate synthase subunit beta | 2.29E-14 | 0.49 |
metF | 5,10-methylenetetrahydrofolate reductase | 1.57E-23 | 0.41 |
HAPS_RS07890 | F0F1 ATP synthase subunit epsilon | 4.18E-29 | 0.13 |
Ribosome | |||
rpmE | 50S ribosomal protein L31 | 6.11E-17 | 0.48 |
HAPS_RS05815 | MULTISPECIES: 30S ribosomal protein S21 | 1.11E-06 | 0.34 |
rpmH | MULTISPECIES: 50S ribosomal protein L34 | 2.28E-07 | 0.47 |
rpmG | MULTISPECIES: 50S ribosomal protein L33 | 1.52E-11 | 0.46 |
ABC transporters | |||
metN | D-methionine ABC transporter, ATP-binding protein | 2.19E-32 | 0.35 |
HAPS_RS08310 | hypothetical protein | 6.04E-14 | 0.31 |
HAPS_RS02205 | methionine ABC transporter permease | 2.49E-15 | 0.46 |
metQ | membrane protein | 5.79E-15 | 0.46 |
HAPS_RS07265 | biotin transporter BioY | 1.06E-30 | 0.31 |
