Figure 7 | Scientific Reports

Figure 7

From: Knockdown of HIF-1α by siRNA-expressing plasmid delivered by attenuated Salmonella enhances the antitumor effects of cisplatin on prostate cancer

Figure 7

Systemic toxicity caused by HIF-1α siRNA and/or DDP treatment in mice. (a) Mean body weights. (b) H&E staining of the heart, liver, spleen, lung, and kidney, 40 days following various treatments as indicated (scale bars = 25 µm). (c) Effects of various treatments on activity of serum ALT and AST. Data were presented as mean ± SD (n = 6).

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