Figure 6
From: Predictable Chronic Mild Stress during Adolescence Promotes Fear Memory Extinction in Adulthood
PCMS during adolescence increased Bdnf gene transcription and decreased the level of Bdnf DNA methylation in the IL. (a) Experimental timeline. (b) Total mRNA levels of Bdnf in the IL. (c–f) Levels of DNA methylation and unmethylation of Bdnf at exons I, II, IV, and VI in the IL. The data are expressed as the mean±SEM (n = 10 per group). *p < 0.05, compared with the control group.
