Figure 6 | Scientific Reports

Figure 6

From: Inhibition of Endoplasmic Reticulum Stress Preserves the Integrity of Blood-Spinal Cord Barrier in Diabetic Rats Subjected to Spinal Cord Injury

Figure 6

Inhibiting ER stress attenuates the adverse effects of diabetes in BSCB disruption after SCI. After SCI, barrier permeability was measured 1d after injury, using EB dye in SCI, SCI + DM and SCI + DM + PBA group. (A,B) Representative whole spinal cords and quantification of BSCB permeability data in each group showing EB dye permeabilized into the spinal cord, n = 4. (C,D) Representative confocal images of EB extravasation and quantification of the fluorescence intensity of EB in each group, n = 4. Scale bar = 1 mm. *p < 0.05, **p < 0.01 vs SCI group, ##p < 0.01 vs SCI + DM group.

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